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Midazolam respiratory risk — DipIMC MCQ

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HardPharmacologyMidazolam respiratory riskDipIMC

A 59-year-old has repeated seizures after head injury. He is hypoxic with snoring respirations and has already received one benzodiazepine dose from carers. What is the most appropriate drug/dose?

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Correct answer: EPrioritise airway support and give further benzodiazepine primarily if seizure activity continues within protocol

Prioritise airway support and give further benzodiazepine primarily if seizure activity continues within protocol is the best answer because benzodiazepines can worsen respiratory depression, so airway support and protocol dosing are essential. Give nebulised salbutamol as first-line trauma therapy is less appropriate because bronchodilator therapy does not address the traumatic pathology; Withhold the drug until laboratory confirmation is available is less appropriate because waiting for tests delays time-critical pre-hospital treatment. Give oral medication and reassess at hospital and Give intramuscular morphine 20 mg as a fixed dose are also suboptimal because they move attention away from the key pre-hospital priority.. The key DipIMC principle is to treat immediate reversible threats, communicate clearly and move the patient toward the right definitive care.

Reference: JRCALC Guidelines; NICE Epilepsies guidance