skip to main content

Major trauma pre-alert — DipIMC MCQ

Instant feedback + full explanation. One question, done properly.

HardTraumaMajor trauma pre-alertDipIMC

An adult taking warfarin has major-trauma haemorrhage and needs emergency reversal in hospital. Which product does NICE recommend immediately?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Prothrombin complex concentrate for immediate reversal

The best answer is “Prothrombin complex concentrate for immediate reversal”. NICE recommends immediate prothrombin complex concentrate for an adult with major-trauma bleeding who needs emergency reversal of a vitamin K antagonist and advises against plasma for this purpose. Vitamin K is also needed for sustained reversal under the hospital protocol. Protamine reverses heparin, platelets do not reverse warfarin and tranexamic acid cannot replace factor repletion.

Reference: NICE NG39, Major trauma: https://www.nice.org.uk/guidance/ng39/chapter/recommendations