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MDMA hyperthermia — DipIMC MCQ

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ModerateMedical EmergenciesMDMA hyperthermiaDipIMC

A 19-year-old woman at a nightclub is hot, agitated and confused after taking tablets sold as MDMA. Temperature is 40.2°C and she has muscle rigidity. What is the most appropriate immediate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Begin active cooling, support ABCs and arrange urgent transfer

Severe hyperthermia after stimulant use is life-threatening and needs immediate cooling, supportive care and urgent transfer. Delaying treatment for a perfect history risks organ failure. Walking and blanket wrapping increase heat production or reduce heat loss. The pearl is that temperature is a vital sign in toxicological agitation.

Reference: JRCALC Guidelines 2025; TOXBASE principles