Anaphylaxis — DipIMC MCQ
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Correct answer: E — Give 500 micrograms adrenaline IM into the anterolateral thigh
The best answer is “Give 500 micrograms adrenaline IM into the anterolateral thigh”. Airway, breathing and circulatory compromise after likely allergen exposure is anaphylaxis. The adult first-line dose is 500 micrograms IM into the anterolateral thigh, repeated after five minutes if compromise persists, alongside positioning, oxygen, monitoring, IV access and crystalloid when indicated. IV bolus adrenaline is hazardous in a patient with a pulse and should not replace the recommended IM route.
Reference: Resuscitation Council UK, Emergency treatment of anaphylaxis: https://www.resus.org.uk/library/additional-guidance/guidance-anaphylaxis/emergency-treatment-anaphylactic-reactions