STEMI — DipIMC MCQ
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Correct answer: B — Give aspirin 300 mg orally as a loading dose
The best answer is “Give aspirin 300 mg orally as a loading dose”. NICE recommends a 300 mg aspirin loading dose as soon as acute coronary syndrome is suspected unless aspirin is contraindicated. A maintenance dose is not an adequate loading regimen, and troponin confirmation must not delay STEMI care. Choice and timing of an additional P2Y12 inhibitor depend on the reperfusion plan, bleeding risk and receiving pathway, so it is not a universal substitute for aspirin.
Reference: NICE CG95, Recent-onset chest pain: https://www.nice.org.uk/guidance/cg95/chapter/recommendations