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Sheehan syndrome — SCE Endocrinology MCQ

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ModeratePituitarySheehan syndromeSCE Endocrinology

A 25-year-old woman has fatigue and headache after postpartum haemorrhage requiring transfusion. She cannot lactate and has amenorrhoea. Sodium is 130 mmol/L and morning cortisol is low. What is the most likely diagnosis?

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Correct answer: E — Sheehan syndrome

Postpartum haemorrhage followed by failure to lactate, amenorrhoea and pituitary hormone deficiencies suggests Sheehan syndrome. Postpartum thyroiditis would not explain cortisol deficiency or agalactia. Glucocorticoid replacement takes priority if ACTH deficiency is present.

Reference: Society for Endocrinology Pituitary Guidance