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Polycystic ovary syndrome — SCE Endocrinology MCQ

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EasyReproductive EndocrinologyPolycystic ovary syndromeSCE Endocrinology

A 23-year-old woman has oligomenorrhoea, acne and hirsutism. BMI is 34 kg/m2. Testosterone is mildly raised, 17-hydroxyprogesterone is normal and pelvic ultrasound shows increased ovarian follicle number. What is the most likely diagnosis?

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Correct answer: B — Polycystic ovary syndrome

Oligo-ovulation with clinical/biochemical hyperandrogenism and polycystic ovarian morphology supports PCOS after excluding mimics. Normal 17-hydroxyprogesterone argues against non-classic CAH. Markedly high testosterone or rapid virilisation would suggest a tumour.

Reference: International PCOS Guideline; NICE CKS PCOS