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Kallmann syndrome — SCE Endocrinology MCQ

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ModeratePituitaryKallmann syndromeSCE Endocrinology

A 28-year-old woman has amenorrhoea, low oestradiol, low LH and FSH, and anosmia since childhood. MRI shows hypoplastic olfactory bulbs. What is the most likely diagnosis?

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Correct answer: E — Kallmann syndrome

Hypogonadotropic hypogonadism with anosmia and olfactory bulb hypoplasia is Kallmann syndrome. Turner syndrome causes hypergonadotropic hypogonadism. PCOS usually has preserved or raised LH with androgen excess, not anosmia.

Reference: Endocrine Society Hypogonadism Guidance