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MEN2B — SCE Endocrinology MCQ

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ModerateNET/MENMEN2BSCE Endocrinology

A 32-year-old man has mucosal neuromas, marfanoid habitus and medullary thyroid carcinoma. Calcium is normal and he has episodic hypertension. What is the most likely diagnosis?

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Correct answer: CMEN2B

MEN2B presents with medullary thyroid carcinoma, mucosal neuromas, marfanoid habitus and phaeochromocytoma risk. Hyperparathyroidism is less typical than in MEN2A. Early recognition affects relatives because RET testing guides prophylactic thyroidectomy.

Reference: Endocrine Society MEN2 Guidance