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Glucocorticoid-induced osteoporosis — SCE Endocrinology MCQ

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EasyCalcium/BoneGlucocorticoid-induced osteoporosisSCE Endocrinology

A 44-year-old man has low-trauma vertebral fractures. He is taking prednisolone 20 mg daily for vasculitis and has normal calcium, phosphate and PTH. What is the most likely contributor?

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Correct answer: CGlucocorticoid-induced osteoporosis

Long-term systemic glucocorticoids are a major cause of secondary osteoporosis and vertebral fracture. Normal calcium and PTH make hyperparathyroidism unlikely. Fracture prevention should be assessed early when long-term steroids are prescribed.

Reference: NICE CG146; NOGG Guideline; BNF