Toxic adenoma — SCE Endocrinology MCQ

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EasyThyroidToxic adenomaSCE Endocrinology

A 36-year-old woman has thyrotoxicosis and a 3 cm solitary hot nodule on radionuclide scan. TSH receptor antibody is negative. What is the most likely diagnosis?

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Correct answer: D — Toxic adenoma

A solitary hyperfunctioning nodule with suppressed TSH is typical of toxic adenoma. Graves' disease usually gives diffuse uptake and positive antibodies. Hot nodules are rarely malignant, but clinical and ultrasound context still matters.

Reference: NICE NG145; British Thyroid Association Guidelines