Postpartum thyroiditis — SCE Endocrinology MCQ

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ModerateThyroidPostpartum thyroiditisSCE Endocrinology

A 28-year-old woman presents 4 months after delivery with anxiety and weight loss. TSH is <0.01 mU/L, free T4 is 28 pmol/L, TSH receptor antibody is negative and radioiodine uptake is low. What is the most likely diagnosis?

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Correct answer: C — Postpartum thyroiditis

Postpartum thyroiditis is a destructive autoimmune thyroiditis with low uptake and negative TSH receptor antibody. Graves' disease postpartum is possible but usually has positive antibodies and higher uptake. Management is usually symptomatic during the thyrotoxic phase, with follow-up for hypothyroidism.

Reference: NICE NG145; BNF