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Alzheimer's disease — DGM MCQ

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EasyDementiaAlzheimer's diseaseDGM

A 79-year-old woman has progressive memory problems over 18 months. She repeats questions, misplaces objects and struggles with finances. Language and visuospatial function are relatively preserved early. Current medicines include amlodipine and atorvastatin. What is the most likely diagnosis?

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Correct answer: E — Alzheimer's disease

Insidious progressive episodic memory impairment in late life is most consistent with Alzheimer's disease. Delirium is acute and fluctuating, frontotemporal dementia often begins with behavioural or language change, normal pressure hydrocephalus has gait and urinary features, and depression requires mood features driving cognition. Collateral history about tempo is essential in cognitive assessment.

Reference: NICE NG97