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De-prescribing statin end-of-life — DGM MCQ

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ModeratePolypharmacyDe-prescribing statin end-of-lifeDGM

A 91-year-old man with metastatic cancer and frailty is reviewed for pill burden. He has difficulty swallowing tablets and prioritises comfort. There is no recent acute coronary syndrome. Current medicines include atorvastatin, morphine, senna and haloperidol as needed. Which medication should be reviewed?

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Correct answer: B — Atorvastatin

Preventive medicines such as statins may be reviewed when prognosis is limited and tablet burden conflicts with goals of care. Morphine and senna address current symptom control, while occasional haloperidol may be appropriate for nausea or agitation if indicated. Deprescribing should be framed around benefit horizon and patient priorities.

Reference: NICE NG56; NICE NG31