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Warfarin interaction — DGM MCQ

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ModeratePolypharmacyWarfarin interactionDGM

An 84-year-old man on stable anticoagulation develops bruising after starting an antibiotic. INR is 6.4 and he has no major bleeding. He was treated for cellulitis this week. Current medicines include warfarin, flucloxacillin and amlodipine. Which medication should be reviewed?

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Correct answer: A — Warfarin interaction and anticoagulation plan

A supratherapeutic INR with bruising after an antibiotic requires warfarin interaction review and anticoagulation management. Amlodipine, colecalciferol, occasional paracetamol and macrogol do not explain the INR rise as directly. Warfarin requires careful monitoring when acute illness or antibiotics occur.

Reference: BNF