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PPI review — DGM MCQ

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ModeratePolypharmacyPPI reviewDGM

A 78-year-old woman asks for a medication review after taking acid suppression for several years. She has no current dyspepsia, ulcer history or gastroprotection indication. Magnesium is low and she has recurrent diarrhoea. Current medicines include omeprazole, amlodipine and levothyroxine. Which medication should be reviewed?

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Correct answer: B — Omeprazole

Long-term PPI therapy without a current indication should be reviewed because of adverse effects and interaction burden. Amlodipine, levothyroxine, paracetamol and colecalciferol have clearer ongoing indications or do not explain the scenario. Deprescribing should consider indication, rebound symptoms and gastroprotection need.

Reference: STOPP/START criteria v3; BNF