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Medication-related bradycardia — DGM MCQ

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HardPolypharmacyMedication-related bradycardiaDGM

An 80-year-old man has falls and presyncope. Pulse is 42 beats/min and ECG shows sinus bradycardia. He has glaucoma and Alzheimer's disease. Current medicines include donepezil, timolol eye drops and amlodipine. Which medication should be reviewed?

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Correct answer: ADonepezil and timolol eye drops

Donepezil and topical beta-blocker eye drops can both contribute to bradycardia and presyncope. Amlodipine is less likely to cause marked bradycardia, and colecalciferol, macrogol and emollient do not fit. Eye drops can have systemic adverse effects in older adults.

Reference: BNF; STOPP/START criteria v3