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Postmenopausal bleeding referral — DRCOG MCQ

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HardGynaecological OncologyPostmenopausal bleeding referralDRCOG

At booking, a woman has a previous unprovoked proximal deep-vein thrombosis and is not on long-term anticoagulation. What thromboprophylaxis should be offered during pregnancy?

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Correct answer: EAntenatal low-molecular-weight heparin throughout pregnancy

The best answer is “Antenatal low-molecular-weight heparin throughout pregnancy”. RCOG advises antenatal thromboprophylaxis with low-molecular-weight heparin for women with previous venous thromboembolism, apart from the specific lower-risk exception of a single event related to major surgery with no other risk factors. This history is unprovoked and therefore needs antenatal rather than postnatal-only prophylaxis.

Reference: RCOG Green-top Guideline No. 37a: Reducing the Risk of Thrombosis and Embolism during Pregnancy and the Puerperium: https://www.rcog.org.uk/guidance/browse-all-guidance/green-top-guidelines/reducing-the-risk-of-thrombosis-and-embolism-during-pregnancy-and-the-puerperium-green-top-guideline-no-37a/