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Down syndrome screening — DRCOG MCQ

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HardAntenatal CareDown syndrome screeningDRCOG

At 11+4 weeks, a woman asks about first-trimester screening for trisomies. What is the most appropriate investigation?

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Correct answer: A — Offer combined screening during the current visit

Combined screening is offered in the first trimester within the screening window and includes nuchal-translucency measurement with maternal serum markers. It is distinct from infection tests and the mid-pregnancy anomaly scan.

Reference: NICE NG201: Antenatal screening: https://www.nice.org.uk/guidance/ng201/chapter/recommendations