Serial hCG — DRCOG MCQ

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EasyEarly PregnancySerial hCGDRCOG

A 25-year-old woman has a positive pregnancy test, pain and no pregnancy seen in the uterus or adnexa. What is the most appropriate investigation?

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Correct answer: A — Serum hCG repeated after 48 hours

Serum hCG repeated after 48 hours is the best answer because the vignette is testing Serial hCG and the recommended approach is consistent with NICE NG126. The other tests may be useful in different pathways, but they would not be the most direct first investigation for this presentation. Specifically, Urine pregnancy test; Chlamydia and gonorrhoea NAAT; Newborn bilirubin measurement; Thyroid function tests would be suboptimal in this scenario. The first investigation should answer the immediate clinical question and follow the relevant UK pathway.

Reference: NICE NG126