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Alcohol use disorder pharmacotherapy — USMLE Step 3 MCQ

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ModeratePsychiatry (outpatient management)Alcohol use disorder pharmacotherapyUSMLE Step 3

A 44-year-old man with alcohol use disorder returns after medically supervised withdrawal. He has not used opioids, has normal liver enzymes, and wants medication to reduce relapse. He is engaged in counselling. Which of the following would you recommend at the follow-up visit?

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Correct answer: COffer naltrexone for relapse prevention

Naltrexone is an evidence-based medication for alcohol use disorder relapse prevention in appropriate patients without current opioid use or severe hepatic contraindication.

Reference: APA alcohol use disorder pharmacotherapy guideline