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SSRI sexual dysfunction — USMLE Step 3 MCQ

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ModeratePsychiatry (outpatient management)SSRI sexual dysfunctionUSMLE Step 3

A 33-year-old man with major depressive disorder has remission on sertraline for 4 months but reports bothersome delayed ejaculation and reduced libido. He has no suicidal ideation or manic symptoms. He wants to continue depression treatment. Which of the following is the most appropriate at this time?

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Correct answer: C — Discuss dose reduction, switching, or adding bupropion after shared decision-making

SSRI sexual adverse effects are common; management includes shared decisions about dose adjustment, switching antidepressants, or adding agents such as bupropion when clinically appropriate.

Reference: APA depression guideline