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Positive depression screen — USMLE Step 3 MCQ

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EasyAmbulatory Medicine / Primary CarePositive depression screenUSMLE Step 3

A 36-year-old woman scores 15 on the PHQ-9 during a wellness visit. She reports low mood, poor sleep, and reduced appetite for 2 months. She denies suicidal ideation, mania, psychosis, and substance misuse. Her thyroid-stimulating hormone level and complete blood count are normal. Which of the following is the most appropriate at this time?

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Correct answer: C — Begin evidence-based psychotherapy, pharmacotherapy, or both after shared decision-making

Moderate major depression in primary care is treated with psychotherapy, antidepressant medication, or both, guided by severity and patient preference.

Reference: APA depression guideline