skip to main content

HIV preexposure prophylaxis — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateAmbulatory Medicine / Primary CareHIV preexposure prophylaxisUSMLE Step 3

A 26-year-old man has sex with men and had rectal gonorrhea twice in the past year. HIV antigen-antibody testing is negative, creatinine is normal, and hepatitis B serology shows immunity. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Offer HIV preexposure prophylaxis with adherence and follow-up testing

Persons at increased risk for HIV acquisition should be offered effective PrEP with routine monitoring.

Reference: USPSTF HIV PrEP Recommendation