Heart failure with reduced ejection fraction — USMLE Step 3 MCQ
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ModerateInternal Medicine (chronic management)Heart failure with reduced ejection fractionUSMLE Step 3
Educational content. Not a substitute for clinical judgement or local policy.
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Correct answer: B — Start sacubitril-valsartan after appropriate ACE inhibitor washout if needed
Guideline-directed therapy for HFrEF includes ARNI therapy when tolerated, in addition to beta-blocker and other foundational agents.
Reference: ACC/AHA/HFSA Heart Failure Guideline