A 56-year-old woman with type 2 diabetes and heart failure started empagliflozin 1 month ago. She now has vulvar itching and thick white discharge.

Question

A 56-year-old woman with type 2 diabetes and heart failure started empagliflozin 1 month ago. She now has vulvar itching and thick white discharge. Wet mount shows budding yeast. Her glucose control has improved. Which of the following is the most likely explanation for this patient's findings?

Accepted Answer

Glucosuria promoting Candida overgrowth

Answer

Hypoglycemia-induced vaginal atrophy

Answer

Immune suppression from beta-cell regeneration

Answer

Direct estrogen receptor blockade

Answer

Renal tubular potassium loss causing discharge

SGLT2 inhibitor genital mycotic infection — USMLE Step 3 MCQ

A 56-year-old woman with type 2 diabetes and heart failure started empagliflozin 1 month ago. She now has vulvar itching and thick white discharge. Wet mount shows budding yeast. Her glucose control has improved. Which of the following is the most likely explanation for this patient's findings?