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Postpartum depression — USMLE Step 3 MCQ

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ModerateOB/GYN (prenatal care, contraception, screening)Postpartum depressionUSMLE Step 3

A 32-year-old woman is seen 4 weeks after delivery with persistent sadness, poor sleep unrelated to infant care, guilt, and low appetite. She denies thoughts of harming herself or the infant and is breastfeeding. Which of the following is the most appropriate next step in management?

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Reveal the answer and explanation

Correct answer: CStart psychotherapy and consider an SSRI compatible with breastfeeding

Postpartum depression should be treated; psychotherapy and selected SSRIs can be compatible with breastfeeding.

Reference: ACOG perinatal mental health guidance