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Bipolar disorder — USMLE Step 3 MCQ

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ModeratePsychiatry (outpatient management)Bipolar disorderUSMLE Step 3

A 28-year-old man has decreased need for sleep, pressured speech, increased goal-directed activity, and risky spending for 9 days. He had a similar hospitalization 2 years ago and currently takes sertraline. Which of the following is the most appropriate next step in management?

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Correct answer: DStop the antidepressant and start a mood stabilizer or antipsychotic

Mania in bipolar disorder requires mood-stabilizing treatment; antidepressant monotherapy may worsen mania.

Reference: APA bipolar disorder treatment guidance