Postpartum gestational diabetes follow-up — USMLE Step 3 MCQ
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Correct answer: B — Give immediate-release oral nifedipine promptly and administer magnesium sulfate for seizure prophylaxis
The best answer is “Give immediate-release oral nifedipine promptly and administer magnesium sulfate for seizure prophylaxis”. Persistent postpartum pressure at or above 160/110 is an emergency requiring rapid treatment. Immediate-release nifedipine is a first-line option and avoids the bradycardia and bronchospasm concerns that make labetalol poorly matched here. Severe neurologic features support magnesium sulfate for eclampsia prophylaxis. Longer-acting outpatient therapy and diuresis may have later roles but cannot replace immediate pressure and seizure-risk control.
Reference: ACOG Severe Hypertension in Pregnancy Bundle: https://www.acog.org/community/districts-and-sections/district-ii/programs-and-resources/safe-motherhood-initiative/severe-hypertension