skip to main content

Breast cancer screening — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

HardPreventive Medicine, Epidemiology, BiostatisticsBreast cancer screeningUSMLE Step 3

A healthy 43-year-old woman has average breast-cancer risk and a normal examination. Her prior screening mammogram at age 41 was negative but reported heterogeneously dense breasts. She asks for annual MRI instead of another mammogram. Which recommendation best reflects current USPSTF guidance?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: EContinue biennial mammography and discuss the uncertain benefit of supplemental dense-breast imaging

The best answer is “Continue biennial mammography and discuss the uncertain benefit of supplemental dense-breast imaging”. USPSTF recommends biennial mammography from ages 40 through 74 for average-risk women. Dense breasts alone do not remove that recommendation, and evidence is insufficient to recommend for or against routine supplemental MRI or ultrasound after an otherwise negative mammogram.

Reference: USPSTF: Breast Cancer Screening: https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening