skip to main content

Uncomplicated cystitis — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

EasyAmbulatory Medicine / Primary CareUncomplicated cystitisUSMLE Step 3

A 27-year-old nonpregnant woman has dysuria, frequency, and suprapubic discomfort for 2 days. She is afebrile with no flank pain or vaginal discharge. Urinalysis shows leukocyte esterase and nitrites. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: DNitrofurantoin therapy for 5 days

Acute uncomplicated cystitis can be treated empirically; nitrofurantoin is a first-line option when pyelonephritis is not suspected.

Reference: IDSA UTI Guidance