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Celiac disease — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Celiac diseaseUSMLE Step 3

A 35-year-old woman has chronic bloating, diarrhea, and iron deficiency anemia. BMI is 19 kg/m2. Tissue transglutaminase IgA is positive and total IgA is normal. Which of the following is the most likely diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BCeliac disease

Diarrhea, iron deficiency, and positive tissue transglutaminase IgA support celiac disease.

Reference: ACG Celiac Disease Guideline