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Post-cholecystectomy diarrhea — USMLE Step 3 MCQ

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ModerateSurgery (post-operative, follow-up)Post-cholecystectomy diarrheaUSMLE Step 3

A 44-year-old woman returns 3 months after laparoscopic cholecystectomy. She has watery diarrhea soon after fatty meals but no fever, blood, weight loss, or nocturnal symptoms. Basic laboratory tests are normal. Which of the following would you recommend at the follow-up visit?

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Correct answer: C — Trial of a bile acid sequestrant

Post-cholecystectomy diarrhea can result from bile acid malabsorption and often responds to bile acid sequestrants.

Reference: American Gastroenterological Association chronic diarrhea guidance