skip to main content

Vasomotor menopausal symptoms — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateAmbulatory Medicine / Primary CareVasomotor menopausal symptomsUSMLE Step 3

A 52-year-old woman has bothersome hot flashes and night sweats 8 months after her last menstrual period. She has no history of breast cancer, venous thromboembolism, stroke, or coronary disease. Blood pressure is normal. She has an intact uterus and wants the most effective therapy. Which of the following is the most appropriate at this time?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Combined estrogen-progestin menopausal hormone therapy

Systemic hormone therapy is the most effective treatment for vasomotor symptoms in appropriate candidates; women with a uterus need endometrial protection with a progestin.

Reference: North American Menopause Society hormone therapy statement