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Positive FIT test — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CarePositive FIT testUSMLE Step 3

A 58-year-old man comes for follow-up after a fecal immunochemical test ordered at his annual visit is positive. He has no abdominal pain, weight loss, melena, or hematochezia. He has no family history of colorectal cancer. Vital signs and abdominal examination are normal. Hemoglobin is 13.9 g/dL. Which of the following is the most appropriate at this time?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Diagnostic colonoscopy

Any positive stool-based colorectal cancer screening test requires diagnostic colonoscopy; repeating the stool test can delay diagnosis.

Reference: USPSTF colorectal cancer screening recommendation