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Smoking cessation — USMLE Step 3 MCQ

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EasyAmbulatory Medicine / Primary CareSmoking cessationUSMLE Step 3

A 46-year-old man who smokes 1 pack daily asks for help quitting. He has tried nicotine gum without success. He has no seizure disorder, eating disorder, or current depression. Blood pressure is 124/76 mm Hg and BMI is 27 kg/m2. He is ready to set a quit date. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BPrescribe varenicline with behavioral support

First-line smoking cessation combines behavioral support with pharmacotherapy such as varenicline or nicotine replacement.

Reference: USPSTF tobacco cessation recommendation: https://www.uspreventiveservicestaskforce.org/