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Hypertriglyceridemia — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)HypertriglyceridemiaUSMLE Step 3

A 46-year-old man has fasting triglycerides of 820 mg/dL, LDL cholesterol 92 mg/dL, and A1c 6.4%. He drinks 4 beers nightly. He has no abdominal pain. TSH and creatinine are normal. Which of the following is the most appropriate next step in management?

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Correct answer: EReduce alcohol intake and start triglyceride-lowering therapy

Very high triglycerides increase pancreatitis risk; management includes addressing secondary causes and triglyceride-lowering therapy.

Reference: ACC expert consensus on hypertriglyceridemia: https://www.acc.org/