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HIV screening — USMLE Step 3 MCQ

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EasyAmbulatory Medicine / Primary CareHIV screeningUSMLE Step 3

A 62-year-old divorced man establishes care after moving. He is sexually active with new partners and uses condoms inconsistently. He has never been tested for HIV. He has no fever, weight loss, lymphadenopathy, or rash. Which of the following is the most appropriate screening recommendation?

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Correct answer: C — HIV antigen-antibody screening

Adults ages 15 to 65 and older adults at increased risk should be screened for HIV infection.

Reference: USPSTF A and B Recommendations, 2025-2026: https://www.uspreventiveservicestaskforce.org/uspstf/recommendation-topics/uspstf-a-and-b-recommendations