skip to main content

Hepatocellular carcinoma surveillance — USMLE Step 3 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateInternal Medicine (chronic management)Hepatocellular carcinoma surveillanceUSMLE Step 3

A 61-year-old man with compensated cirrhosis from cured hepatitis C asks about cancer surveillance. He has no ascites or encephalopathy. Platelets are 105,000/mm3 and ultrasound 1 year ago was normal. Which of the following is the most appropriate screening recommendation?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Ultrasound-based surveillance every 6 months

Cirrhosis remains a risk factor for hepatocellular carcinoma despite viral cure; ultrasound-based surveillance is recommended every 6 months.

Reference: AASLD hepatocellular carcinoma guidance: https://www.aasld.org/