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Colorectal cancer screening — USMLE Step 3 MCQ

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EasyAmbulatory Medicine / Primary CareColorectal cancer screeningUSMLE Step 3

A 46-year-old man comes for a new-patient visit. He has no gastrointestinal symptoms, no personal history of polyps, and no family history of colorectal cancer. He does not smoke. Physical examination and CBC are normal. Which of the following is the most appropriate screening recommendation?

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Correct answer: DBegin average-risk colorectal cancer screening now

Average-risk adults should begin colorectal cancer screening at age 45.

Reference: USPSTF A and B Recommendations, 2025-2026: https://www.uspreventiveservicestaskforce.org/uspstf/recommendation-topics/uspstf-a-and-b-recommendations