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Osteoporosis treatment — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Osteoporosis treatmentUSMLE Step 3

A 69-year-old woman has a femoral neck T-score of -2.8 on screening DXA. Calcium is normal, creatinine clearance is 65 mL/min, and 25-hydroxyvitamin D is sufficient. She has no dysphagia or esophageal disease. Which of the following is the most appropriate next step in management?

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Correct answer: CStart oral bisphosphonate therapy

Postmenopausal osteoporosis is treated with antiresorptive therapy such as an oral bisphosphonate if not contraindicated.

Reference: Endocrine Society osteoporosis guideline: https://www.endocrine.org/