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Obesity pharmacotherapy — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareObesity pharmacotherapyUSMLE Step 3

A 43-year-old man with BMI 36 kg/m2 has hypertension and obstructive sleep apnea. He has completed 6 months of dietary and exercise counselling with 3% weight loss. A1c is 5.8%. He asks about additional treatment and has no personal or family history of medullary thyroid carcinoma. Which of the following is the most appropriate at this time?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Discuss anti-obesity pharmacotherapy with continued lifestyle treatment

Adults with BMI at least 30 kg/m2, or at least 27 kg/m2 with comorbidity, may be offered weight-loss medication as adjunctive therapy.

Reference: Endocrine Society pharmacologic management of obesity guideline: https://www.endocrine.org/