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Acute cholecystitis — USMLE Step 3 MCQ

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ModerateSurgery (post-operative, follow-up)Acute cholecystitisUSMLE Step 3

A 49-year-old woman has right upper quadrant pain for 12 hours with fever and nausea. Pain began after a fatty meal and now persists. Examination shows inspiratory arrest with right upper quadrant palpation. WBC count is 15,200/mm3. Which of the following is the most likely diagnosis?

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Correct answer: AAcute cholecystitis

Persistent RUQ pain, fever, leukocytosis, and Murphy sign suggest cystic duct obstruction with acute cholecystitis.

Reference: SAGES acute cholecystitis guidance: https://www.sages.org/