A 71-year-old man with HFrEF returns after spironolactone was added. He feels well. Potassium is 5.8 mEq/L and creatinine has risen from 1.2 to 1.6

Question

A 71-year-old man with HFrEF returns after spironolactone was added. He feels well. Potassium is 5.8 mEq/L and creatinine has risen from 1.2 to 1.6 mg/dL. ECG is normal. Which of the following is the most likely explanation for this patient's findings?

Accepted Answer

Reduced renal potassium excretion from mineralocorticoid receptor blockade

Answer

Respiratory alkalosis shifting potassium extracellularly

Answer

Renal potassium wasting from loop diuresis

Answer

Excess gastrointestinal potassium loss

Answer

Vitamin B12 deficiency

Hyperkalemia from spironolactone — USMLE Step 3 MCQ

A 71-year-old man with HFrEF returns after spironolactone was added. He feels well. Potassium is 5.8 mEq/L and creatinine has risen from 1.2 to 1.6 mg/dL. ECG is normal. Which of the following is the most likely explanation for this patient's findings?