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Stable thyroid nodule — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Stable thyroid noduleUSMLE Step 3

A 45-year-old woman has a 1.2-cm thyroid nodule found on ultrasound. It is solid, hypoechoic, and has irregular margins. TSH is normal. She has no compressive symptoms and no radiation exposure history. Which of the following is the most appropriate at this time?

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Reveal the answer and explanation

Correct answer: APerform ultrasound-guided fine-needle aspiration

Suspicious ultrasound features at appropriate size threshold warrant fine-needle aspiration.

Reference: American Thyroid Association thyroid nodule guideline: https://www.thyroid.org/