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Ulcerative colitis — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Ulcerative colitisUSMLE Step 3

A 28-year-old man has 3 months of bloody diarrhea, urgency, and tenesmus. Colonoscopy shows continuous erythema and friability from the rectum to the sigmoid colon. Biopsy shows mucosal inflammation with crypt abscesses. Which of the following is the most likely diagnosis?

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Correct answer: BUlcerative colitis

Continuous colonic inflammation beginning in the rectum with bloody diarrhea and crypt abscesses is characteristic of ulcerative colitis.

Reference: American College of Gastroenterology ulcerative colitis guideline: https://gi.org/