Wrong-site surgery prevention — USMLE Step 3 MCQ

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HardEthics, Patient Safety, Quality Improvement, Systems-Based PracticeWrong-site surgery preventionUSMLE Step 3

A healthy patient at 37 1/7 weeks presents in October and has not received maternal RSV vaccine. What best protects her infant?

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Correct answer: A — Infant nirsevimab within 1 week after delivery

The best answer is “Infant nirsevimab within 1 week after delivery”. There is insufficient time after 36 6/7 weeks for maternal antibodies to develop and transfer. In most of the continental US, maternal Abrysvo is given once at 32 0/7 through 36 6/7 weeks during September through January; after 36 6/7 weeks, protect the infant with nirsevimab instead. The alternatives use a different threshold, timing, population, or intervention and therefore do not match the clinical facts presented.

Reference: CDC: RSV Vaccine Guidance for Pregnant Women: https://www.cdc.gov/rsv/hcp/vaccine-clinical-guidance/pregnant-people.html