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COPD exacerbation prevention — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)COPD exacerbation preventionUSMLE Step 3

A 70-year-old man with COPD returns after his second outpatient exacerbation this year. He uses a long-acting muscarinic antagonist. Blood eosinophil count is 330/mcL. He quit smoking and completed pulmonary rehabilitation. Which of the following would you recommend at the follow-up visit?

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Correct answer: AEscalate inhaled therapy to include inhaled corticosteroid-containing regimen

Frequent COPD exacerbations with elevated eosinophils support escalation to inhaled corticosteroid-containing therapy.

Reference: GOLD COPD strategy report: https://goldcopd.org/