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Polycystic ovary syndrome — USMLE Step 3 MCQ

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ModerateOB/GYN (prenatal care, contraception, screening)Polycystic ovary syndromeUSMLE Step 3

A 25-year-old woman has irregular menses every 2 to 4 months and unwanted facial hair. BMI is 32 kg/m2. Pregnancy test is negative. TSH and prolactin are normal. Total testosterone is mildly elevated. Which of the following is the most likely diagnosis?

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Correct answer: BPolycystic ovary syndrome

Oligo-ovulation with clinical or biochemical hyperandrogenism after exclusion of common mimics supports PCOS.

Reference: Endocrine Society PCOS guideline: https://www.endocrine.org/