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Recurrent gout prevention — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareRecurrent gout preventionUSMLE Step 3

A 57-year-old man returns 6 weeks after his third gout flare in 1 year. Serum urate is 9.4 mg/dL, creatinine is normal, and he has no tophi. He is not currently in pain and asks how to prevent further attacks. Which of the following would you recommend at the follow-up visit?

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Correct answer: DStart allopurinol with flare prophylaxis

Recurrent gout flares warrant urate-lowering therapy, typically allopurinol, with anti-inflammatory prophylaxis during initiation.

Reference: ACR Gout Guideline